GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs4372836 | 1 | rs4640348 | chr2:28965479 | TRMT61B | chr2:29072690-29093175:- | -0.29 | -5.03 | 7.45E-7 | Body mass index |
| BLCA | cis | rs12908161 | 1 | rs4643294 | chr15:85250253 | LOC388152 | chr15:84867600-84898920:- | -0.25 | -4.2 | 3.37E-5 | Schizophrenia |
| BLCA | cis | rs703842 | 1 | rs4646536 | chr12:58157988 | FAM119B | chr12:58166383-58176323:+ | 0.31 | 4.79 | 2.38E-6 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs4646536 | chr12:58157988 | TSFM | chr12:58176536-58191367:+ | -0.38 | -6.64 | 1.05E-10 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs4646536 | chr12:58157988 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.24 | -4.17 | 3.73E-5 | Multiple sclerosis |
| BLCA | cis | rs2243480 | 1 | rs464895 | chr7:65527106 | CCT6P1 | chr7:65216092-65228661:+ | 0.3 | 3.9 | 0.000113 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs465359 | chr7:65558164 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.8 | 2.27E-6 | Diabetic kidney disease |
| BLCA | cis | rs4660306 | 1 | rs4660306 | chr1:45978675 | CCDC163P | chr1:45960581-45965646:- | 0.8 | 16.28 | 1.11E-45 | Homocysteine levels |
| BLCA | cis | rs2275426 | 1 | rs4660317 | chr1:46326226 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs4660319 | chr1:46341623 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -7 | 1.18E-11 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs4660321 | chr1:46366760 | CCDC163P | chr1:45960581-45965646:- | -0.37 | -6.96 | 1.44E-11 | Body mass index |
| BLCA | cis | rs4660306 | 1 | rs4660870 | chr1:45995231 | CCDC163P | chr1:45960581-45965646:- | -0.72 | -13.87 | 1.01E-35 | Homocysteine levels |
| BLCA | cis | rs2275426 | 1 | rs4660898 | chr1:46402171 | CCDC163P | chr1:45960581-45965646:- | -0.33 | -6.23 | 1.26E-9 | Body mass index |
| BLCA | cis | rs2275426 | 1 | rs4660910 | chr1:46548402 | CCDC163P | chr1:45960581-45965646:- | -0.33 | -6.17 | 1.71E-9 | Body mass index |
| BLCA | cis | rs4663866 | 1 | rs4663300 | chr2:239181491 | LOC151174 | chr2:239133754-239140318:- | 0.46 | 4.5 | 8.92E-6 | Irritable bowel syndrome |